The University of Chicago XROMM (UC-XROMM) Facility makes it possible for researchers to use high speed biplanar digital videofluoroscopy to collect 3D kinematic data from several kinds of structures that are central to research in biomechanics, neuromechanics and orthopedics:
• internal skeletal elements, such as the hyolaryngeal skeleton, or hand bones, to which external markers cannot be attached without disrupting animal function;
• small animals, such as mice, rats, and songbirds which are too small for external markers;
• animals that will only behave in optically opaque environment, such as in the dark, under soil, in water and/or in structurally complex environments;
• internal soft tissue structures, such as muscles, muscular organs or connective tissues.
Biplanar digital videofluoroscopy is an essential component of XROMM (X-ray Reconstruction of Moving Morphology). XROMM integrates biplanar digital videofluoroscopy with CT-scan based reconstruction of morphology to produce high resolution (+ 0.1 mm) reconstructions of movements of biological structures. Developed by evolutionary biologists at Brown University with grants from the Keck Foundation and NSF, XROMM is rapidly expanding field in integrative and clinical biology. (www.xromm.org/)
The power and promise of XROMM is demonstrated by biological research on a range of projects, including jaw kinematics during feeding in fish, pigs, and ducks, rib kinematics of breathing in lizards, limb kinematics of locomotion in humans, pigs, dogs, birds and bats, and muscle architecture dynamics in rats, turkeys, fish and birds (www.xromm.org).
The University of Chicago XROMM Project (UC-XROMM) brings XROMM to the University of Chicago and the broader scientific community in Chicago thanks to funding through a Major Research Instrumentation Grant from NSF and by the Biological Sciences Division, and in collaboration with the University of Chicago Research Computing Center (RCC).